ONGOING Projects
To join our project simply contact the Principal investigator by mail
PANFRAIL
Elderly and obese patients represent a subgroup of fragile and complex patients, leading to an increasing interest in the potential benefits of minimally invasive surgery, especially regarding a demanding procedure like pancreatic surgery. The "PANFRAIL" study (Pancreatic Resections in Frail Patients) aims to conduct a retrospective analysis of surgical outcomes for obese and elderly (frail) patients undergoing pancreatic resections. The hypothesis is that the benefits of robotic techniques and minimally invasive approaches could be advantageous for elderly patients, particularly for demanding surgical procedures such as pancreatoduodenectomy.
The project is organized into two main areas of investigation, resulting in a total of three separate scientific publications:
- Two distinct studies will be conducted from the pancreatoduodenectomy database o The first study will focus on patients aged 80 and above who have undergone pancreatoduodenectomy. o The second study will target pancreatoduodenectomy patients with a Body Mass Index (BMI) > 30.
- Another study will evaluate the outcomes of distal pancreatectomy specifically in patients aged eighty and older.
PI’s: Benedetto Ielpo - ielpo.b@gmail.com
PI’s: Luca Morelli - luca.morelli@unipi.it
ROLADI
Over the past decade, there has been a growing interest in the use of robotic surgery for diverticular disease (DD). The evidence available in the literature is based on retrospective studies and two meta-analyses. To date, the robotic approach offers significant advantages over laparoscopic surgery in terms of conversion rate and shortened hospital stay for the treatment of diverticular disease.
The ROLADI study trial is a prospective observational study promoted by CRSA.
It is a not-for-profit study and it will include patients who have undergone laparoscopic or robotic resection for elective or delayed urgent treatment of diverticular disease of the left-sided and sigmoid colon. Inclusion criteria are: age > 18 years, elective or delayed urgent colorectal resection for left-sided diverticular disease, fully minimally invasive (robotic or laparoscopic) procedures. Exclusion criteria are: age < 18 years, urgent resection for diverticular disease, hybrid minimally invasive resection and conventional open resection. The primary objective is to evaluate whether the robotic approach reduces the rate of conversion to open surgery compared to laparoscopic surgery. Secondary objectives are to assess the difference between the two approaches in terms of the rate of intraoperative and postoperative complications (according to the Clavien and Dindo classification), hospital stay and disease recurrence. Data will be collected in a prospective database using an easy to fill in Google form, also available on mobile" phones.
PI’s Alessandro Giuliani, Andrea Coratti - giu.giuliani86@gmail.com
ROEM
The ROEM study evaluates the safety and feasibility of robotic surgery in emergency settings through a prospective, multicenter observational design. It focuses on conditions like acute diverticulitis, cholecystitis, and obstructed hernias, analyzing intraoperative and postoperative outcomes, recovery metrics, and cost implications. Clinically stable patients over 18 requiring robotic emergency surgery are included, while elective or non-robotic cases are excluded. Data will be analyzed using statistical methods, with oversight and data management, aiming to clarify the role of robotic platforms in emergency care.
PI’s Marco Milone - milone.marco.md@gmail.com
